Which quantity can be calculated using the equation E = mc2? A. The Energy needed to split an atom into separate protons,Neutrons and Electrons B. The Energy needed to split the nucleus into separate protons and neutrons C. The energy needed to remove an electron from an atom D. The Energy needed to add an electron to an atom



[ E=mc² ] is not the way to calculate any of those choices.

If there's any "missing mass" after any of those things has happened, 
then [ E=mc² ] tells you how much energy the mass has become, and
accounts for the missing mass in that way.